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Finding new medicines in nature using artificial intelligence

A startup called Enveda just raised over $300 million to use AI to search for new drugs hidden in plants and microbes. Instead of building medicines from scratch in a lab, they are using machine learning to map the chemical structures found in nature. They currently have drugs in human clinical trials, targeting skin conditions and weight loss maintenance, marking a step toward proving that AI can help turn natural compounds into effective treatments.

Edition № 568Room: Everyday AI23 September 20262 min readSources: 1
Article

Most of the medicines in your cabinet were built from scratch by scientists using trial and error. A startup called Enveda is taking a different approach by using artificial intelligence to hunt for chemical compounds already existing in nature, like those found in plants and microbes, that could be turned into life-saving drugs.

WHAT'S HAPPENING

Enveda has just secured $311 million in new funding to push these nature-inspired drug candidates through human clinical trials. This is a significant step because, while many companies are using technology to speed up research, very few have actually reached the point of testing their results in human patients. The company is currently focusing on drugs for chronic skin conditions and treatments to help people maintain weight loss after they stop using common weight-loss medications.

Searching nature's library

HOW IT WORKS

Normally, drug discovery is like trying to find a specific grain of sand on a massive beach. Scientists identify a biological problem in the body and then spend years testing millions of chemical combinations to see if any of them interact with that problem in a helpful way. Enveda uses artificial intelligence to act as an incredibly fast librarian. Instead of guessing, they train their software to read the chemical signatures of thousands of natural substances. By analyzing the shapes and patterns of these molecules, the AI predicts which ones might be effective at treating specific human diseases. This allows researchers to bypass the early, slow work of trial and error and go straight to testing the most promising natural candidates in the lab.

WHY IT MATTERS

The success of this approach could change how we find cures for difficult diseases. If the software can accurately predict which natural ingredients will work, we might stop relying solely on synthetic chemistry and start tapping into the vast, untapped library of biology that already exists. While there is still a long path between a computer prediction and a medicine on a pharmacy shelf, moving these projects into human trials is the true test of whether the technology works. If these trials succeed, it would prove that AI can do more than just write text or generate images—it could help us uncover the next generation of medicine.

Sources
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